For many years Wendy blamed herself for the abuse she received as a child and the tragic loss of her boyfriend's life... she had every reason to give up.

Jade suffered from chronic and debilitating back pain for years

Margo always struggled with her weight, food, and body image.

At 540 lbs, Ken's life was constant pain and severe depression - his self image was "human garbage" and thought of himself as a "monster". 

Stephanie Kelly has always been one to put others before herself, but when she finally took the time  to take better care of herself, it completely transformed her life.

Jeremy spent 20 years of his life being the worst person he knew and then was inspired to make a change.

From Worst Year to Best Year - Bryan's Incredible 162-pound transformation

As Patrick's life and health deteriorated, he stopped caring and became incredibly depressed.